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It is also important to contact your doctor immediately if, while taking semaglutide, you experience: hoarseness shortness of breath difficulty swallowing a lump or swelling in the neck Indications Having certain health conditions may affect how well semaglutide works, so it is important to tell your doctor if you have any other medical problems, but especially: diabetic retinopathy depression kidney disease digestion problems type 1 diabetes type 2 diabetes (if using Wegovy) thyroid cancer diabetic ketoacidosis pancreatitis Side Effects of Wegovy Some of the mild and common side effects associated with Wegovy include: burping bloating or pain in the abdomen gas indigestion or heartburn dizziness diarrhea headache nausea vomiting constipation fatigue stomach flu These mild side effects often go away within a few days to a couple of weeks, but be sure to talk to your doctor if they become bothersome or worsen